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Medicinteknikportalen LABIB

Lunds Tekniska Högskola

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Helen Soneson, Matematikcentrum LTH presenterar sitt examensarbete 9 oktober 2007

Helen Soneson, Pi03 presenterar sitt examensarbete Strain in the Normal Human Heart Assessed by Velocity Encoded MRI
Svensk titel: Kartläggning av mekanisk töjning i det normala människohjärtat med hastighetskodad MRI

Seminarium tisdagen den 9 oktober kl 10.15 i sal C (matematikhuset)

Abstract
Regional and global function of the heart is a important aspect to analyze, both
in treatment of heart disease but also in the understanding of the normal heart
function. The imaging modality used for this purpose is in this thesis magnetic
resonance imaging.
The aim of this thesis is to build up a normal model of the movement of the heart, analyzed both by displacement and strain. This model is then used to analyze the correspondence between infarct regions and reduced wall motion in patients' hearts. The normal model was built up by velocity encoded two-dimensional MR images acquired in the 2, 3 and 4 chamber projection from 25 healthy adults.
This model was then compared to strain and displacement in hearts with infarcts.
The infarcted regions were well de ned as having a lower strain compared to the normal model. The displacement in the infarcted hearts was also lower, but
not only in the infarcted areas, but also for the whole heart. This makes the strain model a better model than the displacement model to locating dysfunctional regions in a heart.

Handledare: Einar Heiberg, Klinisk fysiologi och Kalle Åström, Matematikcentrum

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